发明名称 |
METHOD FOR EVALUATION OF COMPOUND USING RSK1 |
摘要 |
<p>A method for evaluation of a compound comprising the steps of introducing an RSK1 gene into a cell to prepare a cell capable of expressing RSK1, contacting a compound to be evaluated with the cell, and detecting the specific binding of the compound to RSK1; and a compound given by the method. The compound can be used as a potentiator or cisplatin. The method enables to find a gene which acts specifically on a cell of cancer induced by the abnormality of p53 or enhanced MAPK pathway and to evaluate a compound by using the gene.</p> |
申请公布号 |
EP1892301(A1) |
申请公布日期 |
2008.02.27 |
申请号 |
EP20060747287 |
申请日期 |
2006.06.06 |
申请人 |
BANYU PHARMACEUTICAL CO., LTD. |
发明人 |
MIZUARAI, SHINJI;KOTANI, HIDEHITO;SHIMOMURA, TOSHIYASU;TANIGUCHI, ERI |
分类号 |
C12Q1/02;A61K31/282;A61P35/00;C12N15/09;C12Q1/68;G01N33/15;G01N33/50 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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