发明名称 |
MEANS AND METHODS FOR GENERATING A T CELL AGAINST AN ANTIGEN OF INTEREST. |
摘要 |
<p>The invention provides a method for generating a T cell comprising a T cell receptor capable of specifically binding an antigen of interest, comprising: -providing a hematopoietic stem cell and/or a precursor cell of a T cell with a nucleic acid sequence comprising at least part of a rearranged gene encoding a TCR chain, or a functional equivalent thereof; and-allowing for differentiation of said stem cell and/or precursor cell and generation of at least one T cell derived from said stem cell and/or precursor cell.</p> |
申请公布号 |
EP1891209(A1) |
申请公布日期 |
2008.02.27 |
申请号 |
EP20060747566 |
申请日期 |
2006.06.06 |
申请人 |
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM |
发明人 |
SPITS, HERGEN |
分类号 |
C12N5/10;A61K45/00;C12N5/0783 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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