发明名称 Cytokine inhibitors
摘要 Disclosed are compounds of formula (I) Where Ar<SUB>1</SUB>, X, Y, Q, W, R<SUP>3</SUP>, R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6 </SUP>and R<SUP>y </SUP>are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. The compounds are also useful for treating diseases or conditions related to oncology and anticoagulant or fibrinolytic therapy. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
申请公布号 US7335657(B2) 申请公布日期 2008.02.26
申请号 US20060426603 申请日期 2006.06.27
申请人 BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 发明人 CIRILLO PIER FRANCESCO;GAO DONGHONG AMY;GOLDBERG DANIEL R.;HAMMACH ABDELHAKIM;HAO MING-HONG;KAMHI VICTOR MARC;MOSS NEIL;NETHERTON MATTHEW RUSSELL;QIAN KEVIN CHUNGENG;RALPH MARK STEPHEN;WU LIFEN;XIONG ZHAOMING;AUNGST, JR. RONALD A.
分类号 A61K31/50;A61K31/404;A61K31/4439;A61K31/506;A61K31/513;A61P29/00;C07D239/02;C07D401/12;C07D403/12;C07D413/02;C07D417/02 主分类号 A61K31/50
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