发明名称 |
Method for treating a viral infection related or a chemical toxin related hepatic injury with deltorphin D |
摘要 |
A method of modulating cytokine mediated hepatic injury by administering compound-D SEQ ID NO:1 to a mammal. A concentration of the compound in the range of about 0.5 mg/kg to about 20 mg/kg in a physiologically acceptable formulation blocks a cytokine cascade. A therapeutic method of modulating cytokine mediated acute inflammatory, trauma induced and toxin induced hepatic injury, particularly via tumor necrosis factor modulation, is thus disclosed.
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申请公布号 |
US7335642(B2) |
申请公布日期 |
2008.02.26 |
申请号 |
US20050085919 |
申请日期 |
2005.03.22 |
申请人 |
UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION |
发明人 |
OELTGEN PETER R.;BISHOP PAUL D.;MCCLAIN CRAIG J.;BARVE SHIRISH |
分类号 |
A61K38/10;C07K14/435 |
主分类号 |
A61K38/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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