摘要 |
The present invention discloses an aminothiol compound having a general formula I wherein R<SUP>1</SUP>-R<SUP>5 </SUP>are substitutable ligands. Such compound can perform as a superior catalyst in an asymmetric addition reaction of organic metal compounds and aldehyde. According to the present invention, the aminothiol compound is needed only less than 0.02% based on main reactants to obtain enantioselectivity higher than 98% enantiomeric excess, whereby the asymmetric reactions can become very economic.
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