| 摘要 |
The invention relates to a device for transdermally administering a compound of formula (1), wherein A represents hydrogen or deuterium, R represents a group selected among C-Calkyl, С-Сcycloalkyl, or phenyl, each of which can be substituted by C-Calkoxy, fluoride, chlorine, bromine, iodine, nitro, amino, hydroxy, oxo, mercapto, or deuterium, the С atom marked by і * (asterisk) being provided in the R configuration. The invention is characterized in that the compound of general formula (I) is provided in a polymer matrix and is released at a dose of 0.5 to 20 mg per day through human skin. The invention further relates to the use of said compounds of formula (I) for producing transdermal medicaments. |
