发明名称 ROOM TEMPERATURE STABLE AQUEOUS LIQUID PHARMACEUTICAL COMPOSITION.
摘要 <p>A liquid pharmaceutical composition is contemplated that comprises a pharmaceutically effective amount of a drug dissolved or dispersed in an aqueous medium. The aqueous medium consists essentially of water, about 3% to about 10% w/v polyvinylpyrrolidone, about 60% to about 75% w/v of C<sub>3</sub>-C<sub>6</sub> polyol that includes more than 55% w/v of a non-reducing disaccharide, trisaccharide or tetrasaccharide such as sucrose, optionally about 0.0 1% to about 0.5% w/v of a glycyrrhetic acid, glycyrrhizinate derivative or salt thereof, and one or more flavorants, and preferably includes one or more preservatives. The liquid composition is room temperature stable, and may have a pleasant taste.</p>
申请公布号 MX2007010163(A) 申请公布日期 2008.02.22
申请号 MX20070010163 申请日期 2005.02.25
申请人 BIOMARIN PHARMACEUTICAL, INC. 发明人 EMMETT CLEMENTE;EMIL D. KAKKIS;BHIKU PATEL;KULJIT BHATIA;FRANK L. SORGI
分类号 A61K31/545 主分类号 A61K31/545
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