Fusion proteins of transferrin and IFNß with increased serum half-life or serum stability are disclosed- Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor.
申请公布号
WO2008021412(A2)
申请公布日期
2008.02.21
申请号
WO2007US18099
申请日期
2007.08.14
申请人
BIOREXIS PHARMACEUTICAL CORPORATION;SADEGHI, HOMAYOUN;TURNER, ANDREW, JOHN;PRIOR, CHRISTOPHER, PHILIP
发明人
SADEGHI, HOMAYOUN;TURNER, ANDREW, JOHN;PRIOR, CHRISTOPHER, PHILIP