发明名称 |
METHOD OF MODULATION OF PROTEIN PHOSPHORYLATION-DEPENDENT CONFORMATIONAL TRANSITIONS WITH LOW MOLECULAR WEIGHT COMPOUNDS |
摘要 |
The present patent application discloses a method of identifying or validating a compound that modulates the phosphorylation-dependent activity of a target protein or protein complex, where the target protein or protein complex activity is regulated by phosphorylation, as well as the use of identified compounds for the production of a pharmaceutical preparation especially for thje treatment of cancer, insulin resistance and diabetes. |
申请公布号 |
WO2008019890(A2) |
申请公布日期 |
2008.02.21 |
申请号 |
WO2007EP07424 |
申请日期 |
2007.08.20 |
申请人 |
BIONDI, RICARDO, M.;ENGEL, MATHIAS;MORTEN, FROEDIN |
发明人 |
BIONDI, RICARDO, M.;ENGEL, MATHIAS;MORTEN, FROEDIN |
分类号 |
C12Q1/48;A61K31/00;C07C323/52;G01N33/50;G01N33/574;G06F19/00 |
主分类号 |
C12Q1/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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