发明名称 |
USE OF CERTAIN CHEMICAL COMPOUNDS FOR THE INHIBITION OF THE PEPTIDYL-PROLYL CIS/TRANS ISOMERASE ACTIVITY OF CYCLOPHILINS |
摘要 |
The present invention relates to the use of certain spiro, ketone and carboxylic acid compounds for the inhibition of the peptidyl-prolyl cis/trans isomerase activity of cyclophilins and the use of these compounds for the production of a cosmetic or pharmaceutical composition for the promotion of hair growth or for the treatment or prevention of inflammatory autoimmune diseases, of diseases caused by fungi, of bacterial infections, of viral infections, of diseases caused by parasites, protozoa or worms, of cancer, of diseases of cells, of fibrosing diseases, and of non-neoplastic changes and diseases which are attributable to prions and changes in the structure and function of cellular proteins and cells. |
申请公布号 |
WO2008019823(A2) |
申请公布日期 |
2008.02.21 |
申请号 |
WO2007EP07181 |
申请日期 |
2007.08.14 |
申请人 |
MAX-PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFT E.V.;HEINRICH-HEINE-UNIVERSITAET DUESSELDORF;FISCHER, GUNTER;SCHIENE-FISCHER, CORDELIA;DAUM, SEBASTIAN;KUELLERTZ, GERHARD;BRAUN, MANFRED;FEAUX DE LACROIX, BORIS |
发明人 |
FISCHER, GUNTER;SCHIENE-FISCHER, CORDELIA;DAUM, SEBASTIAN;KUELLERTZ, GERHARD;BRAUN, MANFRED;FEAUX DE LACROIX, BORIS |
分类号 |
A61K31/12;A61K31/136;A61K31/343;A61P3/10;A61P9/00;A61P13/00;A61P17/06;A61P19/02;A61P25/00;A61P25/16;A61P25/28;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P33/00;A61P35/00;A61P37/02 |
主分类号 |
A61K31/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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