MEDICAL DEVICE FOR VESSEL COMPATIBILITY DURING HIGH PRESSUREINFUSION

摘要

The application provides devices that can be used to deliver a therapeuti c agent to a treatment site within the vessel of a patient at increased pres sure, while limiting the contact with and pressure placed on the vessel wall s. Devices according to the application include an expandable structure (100 ) arranged around and on a tube (130) having a lumen (140). The expandable s tructure may include a sealing ring (111) that makes contact with the interi or surface of a vessel to prevent or decrease fluid flow during delivery of a therapeutic agent. This allows delivery of a therapeutic agent with decrea sed risk of injury to the treatment site. The application also provides for large lumen diameters, preventing shearing stress on therapeutic agents such as cell slurries.