BIO SURFACE ACOUSTIC WAVE (SAW) RESONATOR AMPLIFICATION FOR DETECTION OF A TARGET ANALYTE

摘要

The present invention relates generally to a signal amplification method for a SAW resonator microsensor for analyzing test samples, containing target analyte including proteins and nucleic acids. The invention relates to at least one surface acoustic wave resonator unit comprising a plurality of three-dimensional interdigital transducer electrode (IDTE) and reflector micro channels located on a piezoelectric substrate surface. The invention further relates to a change of solid/liquid volume ratio in said three- dimensional micro channels; said changes of the liquid/solid volume ratio can be di rected correlated to the target analyte concentration in a test sample.