| 摘要 |
<p>Disclosed is a method for producing a commercially suitable 1-methylcarbapenem production intermediate (II), which does not comprise a complicated step, while using low-cost raw material. Specifically disclosed is a method for producing an 1-methylcarbapenem production intermediate (II), wherein a compound represented by the general formula (I) below is reacted with imidazole, then reacted with a malonic acid ester, and finally if necessary, subjected to diazotization.</p> |
| 申请人 |
MEIJI SEIKA KAISHA, LTD.;OKUE, MASAYUKI;TAKAHASHI, MASAAKI;ISHIKAWA, ICHIRO;ITO, NOBUO;YAMAGUCHI, HITOSHI;SUMI, SHINJIRO;AJITO, KEIICHI |
发明人 |
OKUE, MASAYUKI;TAKAHASHI, MASAAKI;ISHIKAWA, ICHIRO;ITO, NOBUO;YAMAGUCHI, HITOSHI;SUMI, SHINJIRO;AJITO, KEIICHI |
