发明名称 |
Inhibitors of serine proteases, particularly HCV NS3-NS4A protease |
摘要 |
The present invention relates to peptidomimetic compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. |
申请公布号 |
US2008045480(A1) |
申请公布日期 |
2008.02.21 |
申请号 |
US20070805085 |
申请日期 |
2007.05.22 |
申请人 |
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发明人 |
FARMER LUC J.;PERNI ROBERT B.;PITLIK JANOS;VAN DRIE JOHN H.JR. |
分类号 |
A61K31/40;C12N9/99;A61K31/13;A61K31/42;A61K31/4965;A61K31/695;A61K31/7052;A61K38/00;A61K38/21;A61K45/00;A61P31/12;A61P31/14;A61P43/00;C07D209/56;C07D261/20;C07D401/12;C07D403/12;C07K5/023;C07K5/06;C07K5/08;C07K5/083;C07K5/10;C07K5/103;C07K7/02;C07K7/06 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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