ПРОИЗВОДНЫЕ ПИРИМИДИНА В КАЧЕСТВЕ МОДУЛЯТОРОВ РЕЦЕПТОРА ИНСУЛИНПОДОБНОГО ФАКТОРА РОСТА 1 (IGF-1), ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СПОСОБЫ ПОЛУЧЕНИЯ (ВАРИАНТЫ) И ПРИМЕНЕНИЕ

摘要

The invention provides compounds of formula in which R1, R2, R3 and R4 have the meanings defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.