发明名称 |
METHODS FOR SYNTHESIS OF DICARBAMATE COMPOUNDS AND INTERMEDIATES IN THE FORMATION THEREOF |
摘要 |
<p>Disclosed is a method of making 2-substituted-2-halo-1,3-propanediols via reduction of corresponding malonate compounds. Also disclosed is a method of making 2-substituted-2-halo-1,3-dicarbamate compounds (such as halo derivatives of felbamate, including fluorofelbamate) via reduction of malonate compounds, followed by carbamoylation. Reduction of the malonate compounds is carried out using an electrophilic hydride reagent.</p> |
申请公布号 |
EP1888570(A2) |
申请公布日期 |
2008.02.20 |
申请号 |
EP20060750880 |
申请日期 |
2006.04.20 |
申请人 |
MEDPOINTE HEALTHCARE INC. |
发明人 |
MORTKO, HENRY;HE, WEIXUAN;ANDERSEN, MARC, W.;DOTSE, ANTHONY, K.;LI, JIE |
分类号 |
C07D413/00;C07D241/00;C07D317/00;C07D333/02 |
主分类号 |
C07D413/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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