发明名称 |
Methods and compositions for diagnosing breast cancer |
摘要 |
Mammastatin has an approximate molecular weight of 44 kDa in its inactive, non-phosphorylated form. Normal mammary cells express functional phosphorylated forms having approximate molecular weights of 53 kDa and 49 kDa. Metastatic mammary cells either do not express Mammastatin at all, or do not express the 53 kDa or 49 kDa, phosphorylated forms. Mammary cancer cells are inhibited in their growth by the administration of phosphorylated Mammastatin.
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申请公布号 |
US7332287(B2) |
申请公布日期 |
2008.02.19 |
申请号 |
US20020192915 |
申请日期 |
2002.07.09 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
ERVIN, JR. PAUL R. |
分类号 |
G01N33/53;A61K38/55;A61K45/00;A61K48/00;A61P35/00;C07K14/47;C07K16/18;C12N15/09;C12N15/12;C12Q1/68;G01N33/574 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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