| 摘要 |
A composition comprising colloidal Fe<SUB>3</SUB>O<SUB>4 </SUB>particles coated with streptavidin is disclosed. These particles can be used in a method for separating biotinylated compounds from a solution in which the biotinylated compounds bind to the streptavidin-coated particles which are attracted to a surface by a magnet. Also disclosed is a method for making said streptavidin-coated composition, said method comprising the steps of forming colloidal Fe<SUB>3</SUB>O<SUB>4 </SUB>particles by mixing aqueous FeCl<SUB>2 </SUB>with aqueous FeCl<SUB>3</SUB>, adding aliquots of the mixture to an alkaline solution and adding streptavidin.
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