IMAGING 18F OR 11C-LABELLED ALKYLTHIOPHENYL GUANIDINES.

摘要

The invention provides a compound of formula (I); or a salt or solvate thereof, wherein: R¹ is hydrogen or C_1-4alkyl; R² and R⁴ are each independently selected from C_1-4 alkyl, [¹¹C] C_{1 4}alkyl, and [¹⁸F]-C_1-4 fluoroalkyl provided that at least one of R² and R⁴ is [¹¹C] C_{1 4}alkyl or [¹⁸F]-C_1-4 fluoroalkyl; and R³ is halo. Such compounds having use for imaging central nervous system receptors.