PHARMACEUTICAL FORMULATIONS FOR MINIMIZING DRUG-DRUG INTERACTIONS.

摘要

A pharmaceutical combination for minimizing pharmacokinetic drug-drug interaction is described including a first pharmaceutical component having a particular pharmacokinetic profile in a mammal and a second pharmaceutical component formulated for parenteral administration having an altered pharmacokinetic profile different from the unaltered pharmacokinetic profile of the second pharmaceutical component, which would interfere with the pharmacokinetic profile of the first pharmaceutical component. Due to its altered pharmacokinetic profile, the second pharmaceutical component does not substantially affect the pharmacokinetic profile of the first pharmaceutical component.