发明名称 |
Calcium-independent phospholipases A2, genes thereof and promoter of the same |
摘要 |
Novel calcium-independent phospholipases A<SUB>2</SUB>; genes encoding the same; an antibody against them; an inherent promoter or a regulator gene which comprises a base sequence occurring in intron and inducing site-specific expression in response to an external stimulus; a method of expressing a target protein in response to an external stimulus; and an organism having this gene transferred thereinto. Novel calcium-independent phospholipases A<SUB>2 </SUB>having an amino acid sequence represented by SEQ ID NO: 1, 3 or 5 or an amino acid sequence derived from such an amino acid sequence by the substitution, deletion or addition of one or more amino acids; a gene having a base sequence occurring in an intron and being capable of initiating RNA transcription due to an external stimulus such as a stimulus with kainic acid or an electrical stimulus; a method of regulating expression by using the gene; and an organism having the gene transferred thereinto.
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申请公布号 |
US7332318(B2) |
申请公布日期 |
2008.02.19 |
申请号 |
US20030468519 |
申请日期 |
2003.08.19 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY |
发明人 |
SHIMIZU TAKAO;KISHIMOTO KOJI;WATANABE YASUYOSHI |
分类号 |
C12N9/20;C07K1/00;C12N15/55;C12Q1/34 |
主分类号 |
C12N9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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