发明名称 |
Preparation of biphosphonic acids and salts thereof |
摘要 |
A process for preparing alendronate sodium includes the reaction of gammabutyric acid with phosphorous acid and phosphorus trichioride and subsequent treatment with an aqueous solution of an alkali metal hydroxide, in which the reaction is conducted in liquid ionic solvents.
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申请公布号 |
US7332603(B2) |
申请公布日期 |
2008.02.19 |
申请号 |
US20050512930 |
申请日期 |
2005.07.13 |
申请人 |
CHEMI S.P.A. |
发明人 |
DE FERRA LORENZO;TURCHETTA STEFANO;MASSARDO PIETRO;CASELLATO PAOLO |
分类号 |
C07F9/22;C07F9/38;C07F9/58;C07F9/6506 |
主分类号 |
C07F9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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