发明名称 Viral vectors having tissue tropism for T-lymphocytes, B- and mast cells
摘要 The present invention relates to methods of introducing an expressible non-viral nucleic acid sequence into a T lymphocyte cell, a B-cell, or a mast cell, comprising contacting the cell with a viral particle containing a modified viral coat proteins containing adenoviral amino acid sequence from an adenoviral serotype Ad35 or Ad51 fiber protein, arrays of subpopulations of cells made by such methods, and a method for a ex vivo transduction of a population of cells.
申请公布号 US7332337(B2) 申请公布日期 2008.02.19
申请号 US20010962543 申请日期 2001.09.25
申请人 GALAPAGOS NV 发明人 VAN ES HELMUTH HENDRIKUS GERARDUS;VAN ZUTPHEN MARLIJN;MA LIBIN;HAVENGA MENZO JANS EMKO
分类号 C12N15/09;A61K48/00;C12N15/861 主分类号 C12N15/09
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