GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH

摘要

Synthetic immunomodulatory molecules having a .gamma.L-glutamyl-, a .gamma.D- glutamyl, a .beta.-L-aspartyl, or a .beta.-D-aspartyl moiety at the amino terminus are provided as illustrated by Formula (A). In Formula (A), "n" is 1 or 2, R is hydrogen, acyl or alkyl, and X is an aromatic or heterocyclic amino acid or its dedvative. A particularly preferred embodiment is .gamma.D-glutamyl-L-tryptophan, which has immunomodulatory activity.