PHARMACEUTICAL COMPRISING PYRAZOLONE DERIVATIVE

摘要

Disclosed is a pharmaceutical which is intended to be administered in such a form that can reduce a renal disorder exacerbated upon the administration of a pyrazolone derivative and an antibiotic in combination. A cerebral protective agent for use in a patient who receives the administration with an antibiotic, comprising a pyrazolone derivative (e.g., 3-methyl-1-phenyl-2-pyrazolin-5-one) or a physiologically acceptable salt thereof or a hydrate or solvate of the derivative or salt as an active ingredient, the pyrazolone derivative or physiologically acceptable salt thereof or the hydrate or solvate of the derivative or salt being administered subsequent to the administration of the antibiotic.