发明名称 |
COMPOSITIONS AND METHODS FOR DETECTING CANCER |
摘要 |
<p>The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.</p> |
申请公布号 |
CA2596238(A1) |
申请公布日期 |
2008.02.18 |
申请号 |
CA20072596238 |
申请日期 |
2007.08.17 |
申请人 |
CLEVELAND CLINIC FOUNDATION;UNIVERSITY OF WASHINGTON;UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIO N;UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
OTEY, CAROL A.;POGUEGEILE, KATHERINE L.;CHEN, RU;BRENTALL, TERESA A.;BRONNER, MARY PATRICIA;WHITCOMB, DAVID C. |
分类号 |
C12Q1/68;C07H21/00;C12N15/12;C12P19/34;C12Q1/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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