ORAL DISINTEGRATING TABLET HAVING MASKED BITTER TASTE AND METHOD FOR PRODUCTION THEREOF

摘要

Provided is an oral disintegrating tablet comprising mitiglinide calcium hydrate, which shows reduced bitter taste and rapid disintegrating properties in an oral cavity and can be dissolved in a digestive tract rapidly. The oral disintegrating tablet comprises a) mitiglinide calcium hydrate, b) crystalline cellulose, c) at least one member selected from the group consisting of an aminoalkyl methacrylate copolymer E, polyvinylacetal diethylaminoacetate, an ethyl acrylate/methyl methacrylate copolymer and ethylcellulose as a masking agent, d) a sugar or a sugar alcohol, and e) at least one member selected from corn starch and partially gelatinized starch, and has masked bitter taste.