发明名称 |
BIOADHESIVE DOSAGE FORM OF STEROIDS |
摘要 |
Bioadhesive steroid nanoparticles are used to prepare a rapidly disintegrating solid oral dosage form of steroid. The bioadhesive steroid nanoparticles have a bioadhesive polymer surrounding the steroid nanoparticles and with an average diameter of less than 1000 nm. Hence, the solid oral dosage form, containing the bioadhesive steroid nanoparticles, a disintegrant and an effervescent agent, instantly disintegrates in the oral cavity and adheres on the periodontal pocket and oral mucosa to release steroid rapidly.
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申请公布号 |
US2008038355(A1) |
申请公布日期 |
2008.02.14 |
申请号 |
US20070876347 |
申请日期 |
2007.10.22 |
申请人 |
PHARMACEUTICAL INDUSTRY TECHNOLOGY AND DEVELOPMENT CENTER |
发明人 |
YANG CHIH-CHIANG;LE YUAN-CHIH;LIU CHAO-CHENG |
分类号 |
A61K9/00;A61K31/56;A61P43/00 |
主分类号 |
A61K9/00 |
代理机构 |
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