Methods of Evaluating Efficacy of an Immune Response by Assesing Alpha-1 Integrin Expression

摘要

Disclosed are compositions and methods evaluating efficacy of an immune response by assessing alpha-1 integrin, screening for, and manufacturing those therapeutic agents. Described herein the presence of VLA-1+ (positive) T cells indicates an effective immune response. Also disclosed are methods of screening for antigens that induce the production of VLA-1+ (positive) T cells, methods of isolating the antigens, and methods using the antigens identified in the screening methods to treat a subject with a disease.