PROTEOMIC PATTERNS OF CANCER PROGNOSTIC AND PREDICTIVE SIGNATURES
摘要
The invention provides method for predicting whether a cancer patient will respond to a therapy. Methods of the invention may involve examining protein from a cell of the cancer patient by determining the binding of a panel of antibodies to the protein. Methods of the invention may be used to generate both expression and activation profiles for cells from a cancer patient. Profiles from a cancer patient may then be compared to known profiles for therapy responders and non-responders to predict the individual response of the patient. For example, methods of the invention may be used to determine whether an ovarian or breast cancer patient will respond to a therapeutic protocol.
申请公布号
WO2008019375(A2)
申请公布日期
2008.02.14
申请号
WO2007US75393
申请日期
2007.08.07
申请人
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM;HENNESSY, BRYAN, T., J.;MILLS, GORDON, B.;COOMBES, KEVIN;GONZALEZ-ANGUELO, ANA;CAREY, MARK
发明人
HENNESSY, BRYAN, T., J.;MILLS, GORDON, B.;COOMBES, KEVIN;GONZALEZ-ANGUELO, ANA;CAREY, MARK