| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a recombinant soluble CD14 fragment which is a novel in vivo protein that serves as an antigen for producing an antibody for measuring a soluble CD14 antigen useful as a marker for diagnosing sepsis. <P>SOLUTION: The recombinant soluble CD14 fragment (a) has its N terminal and C terminal corresponding to either of positions 1-17 and either of positions 59-90, respectively, of a particular amino acid sequence, (b) specifically binds to an antibody binding to a peptide consisting of particular 16 amino acid residues, (c) does not specifically bind to a 3C10 antibody and (d) does not bind to LPS. <P>COPYRIGHT: (C)2008,JPO&INPIT</p> |
