| 摘要 |
PROBLEM TO BE SOLVED: To provide an SCF (stem cell factor) binding inhibitor and a bleaching agent, inhibiting SCF binding to a c-kit receptor, useful as pharmaceuticals or cosmetics. SOLUTION: The invention relates to the SCF binding inhibitor comprising compounds represented by following (1)-(3) and a compound selectd from phosphorylated polysacchrides selected from such as phosphorylated mannan oligosaccharide (originated from Y1892), phosphorylated galactans (originated from Y6493) and phosphorylated galactans (originated from Y6502), or salt of the same, as active component. Wherein (1); 7, 8-dihydrofolic acid (1a) and 7, 8-dihydropteroic acid (1b), (2); dGMP(2a) and 1-(5'-phosphoribosyl)-5-amino-4-imidazole carboxamide (2b), (3); phosphoenolpyruvic acid (3a), 2-isopropylmalic acid (3b), and 2-oxobutyric acid (3c). COPYRIGHT: (C)2008,JPO&INPIT
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