发明名称 |
LANGKETTIGE N-ALKYL VERBINDUNGEN UND DEREN OXA-DERIVATE ZUR VERWENDUNG ALS ANITVIRALE MITTEL |
摘要 |
<p>Long chain N-alkyl amino and imino compounds, oxa-substituted derivatives thereof, and pharmaceutical compositions including such compounds are described. The long chain N-alkyl group is a C8-C16 alkyl group. The long chain N-alkyl compounds and oxa-substituted derivatives thereof can be used in the treatment of viral infections, in particular hepatitis B virus or hepatitis C virus, in a cell or an individual. For example, the long chain N-alkyl compounds or oxa-substituted derivatives thereof can be derived from piperidines, pyrrolidines, phenylamines, pyridines, pyrroles, or amino acids.</p> |
申请公布号 |
DE60037664(D1) |
申请公布日期 |
2008.02.14 |
申请号 |
DE2000637664 |
申请日期 |
2000.08.10 |
申请人 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;THOMAS JEFFERSON UNIVERSITY;SYNERGY PHARMACEUTICALS INC. |
发明人 |
ZITZMANN, NICOLE;BUTTERS, TERRY D.;PLATT, FRANCES M.;CARROUEE, SANDRA;JACOB, GARY S;PICKER, DONALD H.;FLEET, GEORGE;DWEK, RAYMOND A;DURANTEL, DAVID;MEHTA, ANAND;BLOCK, TIMOTHY M |
分类号 |
A61K31/435;C07D211/46;A61K31/00;A61K31/13;A61K31/16;A61K31/166;A61K31/195;A61K31/40;A61K31/44;A61K31/445;A61K45/00;A61K51/00;A61P31/12;C07C231/12;C07C237/30;C07D207/12 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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