发明名称 |
COMBINATION OF GYRASE B INHIBITORS AND PROTEIN SYNTHESIS INHIBITORS AND USES THEREOF |
摘要 |
The present invention relates to compounds and methods of treating, preventing, or lessening the severity of drug-resistant Gram-positive bacterial infections in mammals. The compounds consist of a combination of a gyrase B inhibitor and a protein synthesis inhibitor. These compounds demonstrate antibacterial activity against drug-resistant strains of Gram-positive bacteria, and in particular, methicillin-resistant Staphylococcus aureus (MRSA). Methods for inhibiting the activity of strains of Gram-positive bacteria and methods for treating a bacterial infection caused by such organisms are described herein.
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申请公布号 |
WO2007142725(A3) |
申请公布日期 |
2008.02.14 |
申请号 |
WO2007US08057 |
申请日期 |
2007.04.03 |
申请人 |
BATTS, DONALD HERMAN;DEKONING, THOMAS FRANK |
发明人 |
BATTS, DONALD HERMAN;DEKONING, THOMAS FRANK |
分类号 |
A61K31/70;A61K31/35;A61K31/65 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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地址 |
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