| 摘要 |
A nanotube mat containing one or more hydrogels is provided. The nanotube mat/hydrogel device allows for the formation of conduits partially or completely through the thickness of the device. The device could be used as support or host device for biological cells, an agent delivery device or a prosthetic interface. Carbon nanotubes and hydrogels are used to develop the device provide mechanical stability, are biocompatible, will support cell growth, allow for patterning of biological cells, allow its surfaces to be derivatized with growth factors, molecules, nutrients, inhibitory factors, ligands, transduction molecules or morphogenic factors, and would allow the formation of conduits to guide cells, neurites and axons to be hosted or grown. The hydrogel(s) within the device has(have) a dry and a hydrated state useful for creating a film layer at the surfaces of the device (or components thereof) or encapsulating or surrounding the content within the conduits.
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