| 发明名称 |
2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES |
| 摘要 |
The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades. |
| 申请公布号 |
US2008039622(A1) |
申请公布日期 |
2008.02.14 |
| 申请号 |
US20070782581 |
申请日期 |
2007.07.24 |
| 申请人 |
RIGEL PHARMACEUTICALS, INC. |
发明人 |
SINGH RAJINDER;ARGADE ANKUSH;PAYAN DONALD;MOLINEAUX SUSAN;HOLLAND SACHA J.;CLOUGH JEFFREY;KEIM HOLGER;BHAMIDIPATI SOMASEKHAR;SYLVAIN CATHERINE;LI HUI;ROSSI ALEXANDER B. |
| 分类号 |
C07D241/36;A61K31/505;A61K31/506;A61K31/519;A61K31/5377;A61P1/00;A61P11/06;A61P17/00;A61P27/02;A61P27/14;A61P27/16;A61P29/00;A61P37/08;A61P43/00;C07D239/46;C07D239/48;C07D295/00;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D405/12;C07D405/14;C07D409/12;C07D409/14;C07D413/12;C07D413/14;C07D417/12;C07D417/14 |
主分类号 |
C07D241/36 |
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