发明名称 Compounds For Specific Viral Target
摘要 The present application relates to a compound having a formula 1: B-R1-R2-M wherein B is a binding element for recognizing and binding a target; R1 is a first group of atoms for reacting with a functionality of the target so as to form a covalent bond with the target; R2 is a second group of atoms; R1 and R2 being such that the formation of the covalent bond between R1 and the target generates cleavage of the bond between R1 and R2 so as to free R2-M; and M is selected from the group consisting of a hydrogen atom and a pharmaceutically acceptable moiety. Alternatively, R1 and R2 can be inverted to form the formula II: B-R2-R1-M and being such that the formation of the covalent bond between R1 and the target generates cleavage of the bond between R1 and R2 so as to free R2-B.
申请公布号 US2008039532(A1) 申请公布日期 2008.02.14
申请号 US20050579929 申请日期 2005.05.06
申请人 BRIDON DOMINIQUE;BOUSQUET-GAGNON NATHALIE;HUANG XICAI;QURAISHI OMAR 发明人 BRIDON DOMINIQUE;BOUSQUET-GAGNON NATHALIE;HUANG XICAI;QURAISHI OMAR
分类号 A61K47/48;A61K47/42;A61P31/12;C07K14/00;C07K14/005;C07K14/16 主分类号 A61K47/48
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