发明名称 |
Compounds For Specific Viral Target |
摘要 |
The present application relates to a compound having a formula 1: B-R1-R2-M wherein B is a binding element for recognizing and binding a target; R1 is a first group of atoms for reacting with a functionality of the target so as to form a covalent bond with the target; R2 is a second group of atoms; R1 and R2 being such that the formation of the covalent bond between R1 and the target generates cleavage of the bond between R1 and R2 so as to free R2-M; and M is selected from the group consisting of a hydrogen atom and a pharmaceutically acceptable moiety. Alternatively, R1 and R2 can be inverted to form the formula II: B-R2-R1-M and being such that the formation of the covalent bond between R1 and the target generates cleavage of the bond between R1 and R2 so as to free R2-B.
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申请公布号 |
US2008039532(A1) |
申请公布日期 |
2008.02.14 |
申请号 |
US20050579929 |
申请日期 |
2005.05.06 |
申请人 |
BRIDON DOMINIQUE;BOUSQUET-GAGNON NATHALIE;HUANG XICAI;QURAISHI OMAR |
发明人 |
BRIDON DOMINIQUE;BOUSQUET-GAGNON NATHALIE;HUANG XICAI;QURAISHI OMAR |
分类号 |
A61K47/48;A61K47/42;A61P31/12;C07K14/00;C07K14/005;C07K14/16 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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