摘要 |
Disclosed herein are compounds, compositions and methods for modulating DGAT- I activity. Preferably, the expressionof DGAT-I from a nucleic acid is inhibited. Methods are provided for treating, ameliorating or treating liver fibrosis, either directly or by treating an underlying etiological factor. Preferably, the treatment, amelioration or prevention comprises administering a DGAT- I activity modulator. |
申请人 |
ISIS PHARMACEUTICALS, INC.;YU, XIAG-XIAN;BHANOT, SANJAY;MONIA, BRETT, P. |
发明人 |
YU, XIAG-XIAN;BHANOT, SANJAY;MONIA, BRETT, P. |