发明名称 |
OLIGONUCLEOTIDES FOR DISCRIMINATING RELATED NUCLEIC ACID SEQUENCES |
摘要 |
An in vitro selection method is described which identifies oligonucleotide probes that discriminate amongst closely related nucleic acid sequences and which involves iterative hybridizations, including subtractive hybridization. Using the method, oligonucleotides are identified which can discriminate among human papilloma virus (HPV) subtypes. Corresponding methods and kits for the detection of nucleic acids are described, which methods and kits may be used in analytical, diagnostic, research and related applications.
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申请公布号 |
CA2694984(A1) |
申请公布日期 |
2008.02.14 |
申请号 |
CA20072694984 |
申请日期 |
2007.08.10 |
申请人 |
CHU SAINTE-JUSTINE, LE CENTRE HOSPITALIER UNIVERSITAIRE MERE-ENFANT |
发明人 |
BRUKNER, IVAN;KRAJINOVIC, MAJA;LABUDA, DAMIAN |
分类号 |
C07H21/04;C12N15/37;C12P19/34;C12Q1/68;C12Q1/70;C40B40/06 |
主分类号 |
C07H21/04 |
代理机构 |
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