发明名称 |
CRYSTALLIZATION INHIBITOR AND ITS USE IN GELATIN CAPSULES |
摘要 |
<p>The present invention describes soft gelatin capsules that encapsulate a water-insoluble active ingredient and an excipient composed of a crystallization inhibitor that stabilizes the water-insoluble inhibitor. The crystallization inhibitor being at least one mononacylglycerol compound whose acyl group is a fatty acid residue of 6-18 carbon atoms. The capsule contents are more resistant to turbidity, forming a coarse emulsion, and crystallization of the active ingredient compared with compositions absent the crystallization inhibitor.</p> |
申请公布号 |
EP1885342(A1) |
申请公布日期 |
2008.02.13 |
申请号 |
EP20060738862 |
申请日期 |
2006.03.16 |
申请人 |
IVAX PHARMACEUTICALS S.R.O. |
发明人 |
ANDRYSEK, TOMAS;VRANA, ALES |
分类号 |
A61K9/48 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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