A device for multi-dimensional separation and analysis of molecules.

摘要

The device comprises a chamber 12 for subjecting a first substance to a first analysis step and a space 10 for receiving a second substance. The device is configured to apply pressure (for example by mechanical means, gas-compression or hydraulic pressure), to the second substance to move the second substance towards a product of the first analysis step to provide a sample for a second analysis. The device has particular application in 2D electrophoresis. In an embodiment a stopper membrane may be provided between the first substance and the second substance. An electric field may be applied to draw the product of the first step through the stopper membrane into contact with the second substance. In an alternative embodiment the product of the first step may diffuse through the stopper.