发明名称 |
Controlled release compositions for interferon based on block polymers |
摘要 |
<p>The invention discloses a pharmaceutical composition for the controlled release of relatively toxic active compounds, in particular for bioactive proteins from the class of interferons. The composition comprises a biodegradable block copolymer constructed from poly(ethylene glycol) terephthalate (PEGT) and poly(butylene terephthalate) (PBT). The composition is provided in the form of injectable microparticles, of an injectable liquid which may have self-gelling properties, or of a solid implant. The invention further provides a pharmaceutical kit comprising the composition, methods for preparing the composition, and the pharmaceutical uses relating thereto.</p> |
申请公布号 |
EP1886668(A1) |
申请公布日期 |
2008.02.13 |
申请号 |
EP20070120539 |
申请日期 |
2006.01.06 |
申请人 |
BIOLEX THERAPEUTICS, INC. |
发明人 |
BECHET, ANNE C.;VAN DIJKHUIZEN-RADERSMA, RIEMKE;STIGTER, MARTIN;BEZEMER, JEROEN M. |
分类号 |
A61K9/113;A61K9/16;A61K9/19;A61K38/21;A61K47/34;A61P31/12;A61P31/18 |
主分类号 |
A61K9/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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