| 发明名称 |
Methods for real-time single molecule sequence determination |
| 摘要 |
A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
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| 申请公布号 |
US7329492(B2) |
申请公布日期 |
2008.02.12 |
| 申请号 |
US20040007797 |
申请日期 |
2004.12.08 |
| 申请人 |
VISIGEN BIOTECHNOLOGIES, INC. |
发明人 |
HARDIN SUSAN;GAO XIAOLIAN;BRIGGS JAMES;WILLSON RICHARD;TU SHIAO-CHUN |
| 分类号 |
C12Q1/68;G01N21/64;C07H21/02;C07H21/04;C12M1/00;C12N9/10;C12N9/12;C12N9/22;C12N15/09;C12P19/34;C12Q1/70;G01N21/78;G01N33/48;G01N33/50;G01N33/53;G01N33/566;G01N33/58 |
主分类号 |
C12Q1/68 |
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