| 摘要 |
The first subject of this invention is a column packing material comprising: a silica gel having a silanol group; a first chemical modification group which is bound to said silanol group; a silicone polymer for coating the surface of said silica gel; and, a trimethylsilyl group which is bound to the silanol group on said silicone polymer and/or the silanol group on said silica gel. The second subject of this invention is a method for producing a column packing material comprising the following steps (A) to (C): (A) a step for introducing a first chemical modification group into a silanol group on the surface of a silica gel by reacting the silica gel with a silane coupling agent having said first chemical modification group; (B) a step for forming a silicone polymer coating on the surface of said silica gel by polymerizing one or more silicone compounds on the surface of the silica gel after step (A); and, (C) a step for trimethylsilylating a silanol group on said silicone polymer and/or a silanol group on said silica gel using an end-capping agent after step (B). |
