| 发明名称 |
BENZENESULFONATE SALTS OF 4-FLUORO-2-CYANOPYRROLIDINE DERIVATIVES |
| 摘要 |
A benzenesulfonate salt of (2S,4S)-2-cyano-4-fluoro- 1-[(2-hydroxy-1,1-dimethyl)ethylamino]acetylpyrrolidine that has an excellent DPPIV inhibition activity as well as physical properties (e.g., stability) required for pharmaceutical preparations. The present invention allows easy obtaining of the compound in high-purity uniform crystal form with excellent solid-state stability.
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| 申请公布号 |
CA2496623(C) |
申请公布日期 |
2008.02.12 |
| 申请号 |
CA20032496623 |
申请日期 |
2003.08.27 |
| 申请人 |
TAISHO PHARMACEUTICAL CO., LTD. |
发明人 |
FUKUSHIMA, HIROSHI;KAMEO, KAZUYA;HIRATATE, AKIRA;TAKAHASHI, MASATO |
| 分类号 |
C07D207/16;A61K31/40;A61P3/04;A61P3/10;A61P13/08;A61P19/02;A61P19/10;A61P37/00;A61P43/00 |
主分类号 |
C07D207/16 |
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