发明名称 |
Preparation and use of cyclic and branched peptides and their labelled derivatives as therapeutic agents, cholecystokinin agonists or antagonists, and diagnostic agents to identify and locate tumours |
摘要 |
This patent application describes the preparation of cyclic and branched peptides of general formula (I) and their conjugated derivatives labelled with a paramagnetic or radioactive metal. The compounds of the present invention are used as diagnostic agents to identify and locate primary tumours and their metastases which over-express type A and/or B cholecystokinin receptors, and as therapeutic agents and cholecystokinin agonists or antagonists.
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申请公布号 |
US7329644(B2) |
申请公布日期 |
2008.02.12 |
申请号 |
US20040479096 |
申请日期 |
2004.07.16 |
申请人 |
BRACCO IMAGING S.P.A. |
发明人 |
SAVIANO MICHELE;DE LUCA STEFANIA;MORELLI GIANCARLO;TESAURO DIEGO;PEDONE CARLO |
分类号 |
A61K38/00;A61K38/12;A61K49/00;A61K51/00;A61K51/08;A61P35/00;A61P43/00;C07K5/12;C07K7/64;C07K14/00;C07K14/595;G01N33/532;G01N33/534;G01N33/58;G01N33/60 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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