发明名称 |
GAMMARETROVIRUS ASSOCIATED WITH CANCER. |
摘要 |
<p>The present invention provides for isolated nucleic acid sequences encoding viruses; isolated polypeptides comprising amino acid sequences of the virus; vectors comprising the viral nucleic acid sequences; cells comprising the vectors; antibodies and antigen binding fragments thereof which have binding specificity for the virus; methods of detecting or screening for the virus (e.g., in an individual); methods of identifying agents that inhibit the virus; methods of inducing an immune response to the virus; methods of treating disease associated with the presence of XMRV in an individual (e.g., cancer such as prostate cancer); methods of detecting asymptomatic cancer (e.g., prostate cancer); methods of identifying an individual at risk for developing cancer (e.g., prostate cancer); and kits for detecting the virus.</p> |
申请公布号 |
MX2007012361(A) |
申请公布日期 |
2008.02.11 |
申请号 |
MX20070012361 |
申请日期 |
2006.04.07 |
申请人 |
THE CLEVELAND CLINIC FOUNDATION |
发明人 |
SILVERMAN, ROBERT;KLEIN, ERIC, A.;DERISI, JOSEPH;GANEM, DON;CASEY, GRAHAM |
分类号 |
C12N7/00;A61K39/21;C07K14/15;C12N5/10;C12N7/02;C12N15/11;C12N15/63;C12Q1/68;G01N33/50;G01N33/569 |
主分类号 |
C12N7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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