| 发明名称 |
USE OF 3-(3,5-DIOXO-4,5-DIHYDRO-3H-(1,2,4)TRIAZIN-2-YL)-BENZAMIDE DERIVATIVES AS P2X7-INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES |
| 摘要 |
A compound of the formula (1) wherein the values of R¹, R² and R³ are provided in the description, or its pharmaceutically effective salts or solvates or prodrugs, a pharmaceutical composition on its base and use thereof for treatment of IL-1 mediated disorders. Tables: 3 |
| 申请公布号 |
GEP20084304(B) |
申请公布日期 |
2008.02.11 |
| 申请号 |
GE2003AP08875 |
申请日期 |
2003.12.19 |
| 申请人 |
PFIZER PRODUCTS INC. |
发明人 |
DUPLANTIER, ALLEN, JACOB;DOMBROSKI, MARK, ANTHONY |
| 分类号 |
A61K31/53;A61K;A61K31/5377;A61P19/02;C07D;C07D253/02;C07D253/06;C07D253/075;C07D295/02;C07D401/06;C07D405/06 |
主分类号 |
A61K31/53 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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