摘要 |
<p>The method according to the invention is a moulding method wherein a first layer (21), having a first colour, is produced against a first portion of a mould surface (10) and wherein, in a next step, a second layer (22), having a second colour, is produced against a second portion of the mould surface (10) and at least partially against the back of the first layer (21). The method is intended to obtain a qualitative transition between the colours of the two layers (21, 22) without having to hide the actual colour transition in a groove from view. This object is achieved by applying the material forming the first layer (21) in such a manner on the mould surface (10) that the edge (20) of the first layer (21), which will be situated on the mould surface underneath the second layer (22), is visually sharp and is produced without a mask. The method according to the invention is a moulding method wherein a first layer (21), having a first colour, is produced against a first portion of a mould surface (10) and wherein, in a next step, a second layer (22), having a second colour, is produced against a second portion of the mould surface (10) and at least partially against the back of the first layer (21). The method is intended to obtain a qualitative transition between the colours of the two layers (21, 22) without having to hide the actual colour transition in a groove from view. This object is achieved by applying the material forming the first layer (21) in such a manner on the mould surface (10) that the edge (20) of the first layer (21), which will be situated on the mould surface underneath the second layer (22), is visually sharp and is produced without a mask. This invention comprises the novel compounds of formula (I) wherein R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup>, R<sup>4</sup>, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.</p> |