method for synthesis OF 1,3,4,5-TETRAHYDRO-2Н-3-benzazepin-2-Оn COMPOUNDS and usE THEREOF in synthesis OF IvaBRIDIN and additive saltS thereof with pharmacEutically acceptable acid

摘要

A method for the synthesis of compounds of the formula (І):, (I)wherein Rand Rmay be the same or different, each of them is linear or branched (C-C) alkoxy group or form with attached carbon atom 1,3-dioxane, 1,3-dioxolane or 1,3-dioxepane ring. Their use in the synthesis of ivabradinum and additive salts thereof with pharmaceutically acceptable acid and hydrates thereof.